Gene name
Cubn (Ifcr)
Experiment(s)
For this entry:
CUBN_MOUSE (Cubn)
Species | Mus musculus |
---|---|
Localization | Apical plasma membrane |
Reference |
Strope S,Rivi R,Metzger T,Manova K,Lacy E (2004) Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules., Development, 131, 4787-95. [PubMed] [DOI] |
Evidence level | Antibody staining |
Organ | Embryonic epithel |
Cell | Visceral endoderm cells |
Notes | The apical localization of cubilin is dependent on heteromerization with amnionless |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start | End | Localisation |
---|---|---|
1 | 3623 | Extracellular |
Phosphorylation
Glycosylation
Family and domain data
Database | Domain/Family name |
---|---|
InterPro | CUB_dom |
InterPro | EGF-like_Ca-bd_dom |
InterPro | EGF-like_CS |
InterPro | EGF-like_dom |
InterPro | EGF-type_Asp/Asn_hydroxyl_site |
InterPro | EGF_Ca-bd_CS |
InterPro | EGF_dom |
InterPro | Sperma_CUB_dom_sf |
Pfam | CUB |
Pfam | EGF |
Pfam | EGF_3 |
Pfam | EGF_CA |
Pfam | hEGF |