Gene name
COL4A4
Experiment(s)
For this entry:
CO4A4_MOUSE (COL4A4)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Abrahamson DR,Hudson BG,Stroganova L,Borza DB,St John PL (2009) Cellular origins of type IV collagen networks in developing glomeruli., J Am Soc Nephrol, 20, 1471-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Podocytes |
| Notes | Forms a strict heterotrimer alpha3+alpha4+alpha5 |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 1682 | Extracellular |
Phosphorylation
| Position | Resource |
|---|---|
| 554 | 18503537 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Collagen |
| InterPro | Collagen_IV_NC |
| InterPro | Collagen_IV_NC_sf |
| InterPro | CTDL_fold |
| Pfam | C4 |
| Pfam | Collagen |