Gene name
Col4a2
Experiment(s)
For this entry:
CO4A2_HUMAN (Col4a2)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Uhlén M,Fagerberg L,Hallström BM,Lindskog C,Oksvold P,Mardinoglu A,Sivertsson Å,Kampf C,Sjöstedt E,Asplund A,Olsson I,Edlund K,Lundberg E,Navani S,Szigyarto CA,Odeberg J,Djureinovic D,Takanen JO,Hober S,Alm T,Edqvist PH,Berling H,Tegel H,Mulder J,Rockberg J,Nilsson P,Schwenk JM,Hamsten M,von Feilitzen K,Forsberg M,Persson L,Johansson F,Zwahlen M,von Heijne G,Nielsen J,Pontén F (2015) Proteomics. Tissue-based map of the human proteome., Science, 347, 1260419. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes | Inferred from the Tissue Atlas |
CO4A2_HUMAN (Col4a2)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Uhlén M,Fagerberg L,Hallström BM,Lindskog C,Oksvold P,Mardinoglu A,Sivertsson Å,Kampf C,Sjöstedt E,Asplund A,Olsson I,Edlund K,Lundberg E,Navani S,Szigyarto CA,Odeberg J,Djureinovic D,Takanen JO,Hober S,Alm T,Edqvist PH,Berling H,Tegel H,Mulder J,Rockberg J,Nilsson P,Schwenk JM,Hamsten M,von Feilitzen K,Forsberg M,Persson L,Johansson F,Zwahlen M,von Heijne G,Nielsen J,Pontén F (2015) Proteomics. Tissue-based map of the human proteome., Science, 347, 1260419. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Placenta |
| Cell | Trophoblast cells |
| Notes | Inferred from the Tissue Atlas |
CO4A2_HUMAN (Col4a2)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Uhlén M,Fagerberg L,Hallström BM,Lindskog C,Oksvold P,Mardinoglu A,Sivertsson Å,Kampf C,Sjöstedt E,Asplund A,Olsson I,Edlund K,Lundberg E,Navani S,Szigyarto CA,Odeberg J,Djureinovic D,Takanen JO,Hober S,Alm T,Edqvist PH,Berling H,Tegel H,Mulder J,Rockberg J,Nilsson P,Schwenk JM,Hamsten M,von Feilitzen K,Forsberg M,Persson L,Johansson F,Zwahlen M,von Heijne G,Nielsen J,Pontén F (2015) Proteomics. Tissue-based map of the human proteome., Science, 347, 1260419. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Testis |
| Cell | Sertoli cells |
| Notes | Inferred from the Tissue Atlas |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 1712 | Extracellular |
Phosphorylation
Glycosylation
| Position | Site resource | Glycan resource | PubMed link(s) |
|---|---|---|---|
| 111 | dbPTM | 55826745 | |
| 111 | O-GlycoProteomDB | ||
| 111 | PhosphoSitePlus |
![WURCS=2.0/1,1,0/[a2112h-1x_1-5_2*NCC/3=O]/1/](data:image/png;base64,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)
|
|
| 138 | dbPTM | 3198637 | |
| 138 | N-GlycoSiteAtlas | 24495048 | |
| 138 | UniProtKB | 3198637 | |
| 257 | O-GlycoProteomDB | ||
| 265 | O-GlycoProteomDB | ||
| 265 | PolarProtDb |
![WURCS=2.0/2,2,1/[axxxxh-1x_1-5_2*NCC/3=O][axxxxh-1x_1-5]/1-2/a?-b1](data:image/png;base64,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)
|
29296958 |
| 265 | UniCarbKB |
![WURCS=2.0/2,2,1/[uxxxxh_2*NCC/3=O][uxxxxh]/1-2/a?|b?}-{a?|b?](data:image/png;base64,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)
|
30459171 |
| 265 | UniCarbKB |
![WURCS=2.0/1,1,0/[uxxxxh_2*NCC/3=O]/1/](data:image/png;base64,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)
|
30459171 |
| 268 | O-GlycoProteomDB | ||
| 698 | O-GlycoProteomDB | ||
| 1275 | N-GlycoSiteAtlas | 22113853 | |
| 1358 | O-GlycoProteomDB | ||
| 1361 | O-GlycoProteomDB | ||
| 1361 | dbPTM | 55832591 | |
| 1361 | PhosphoSitePlus |
|
|
| 1403 | PolarProtDb |
![WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAIYAAABSCAIAAAAetDv/AAACMklEQVR42u3cL3PCMBzGcTSHQCKRSAQCieCFIBCISgQSgUAgEAheBAKJ4B0gEAgkLwGBqECw3O1ux61tknZr80v4PqqkuWzk0/xpbrfaiwhLzbbeW1ILNbeM7WjK3+++f0ytY9laCCTJ7jNW+7lO9pR9uYYkVTTXb+sxieVX0jzFxs7Sd+L3x8IkAY4StyRZoyp560NJsiZom8c8+Swbr4uRhL+WGAHsSX6hGsuzRl6W5V9GeVAkBSpYlmft6D6dJNcgsJlw7K8t16pcm4XA30v0Pah//8iqX2D78InvJQQSSAgkBBJICCSQEEggIZAQSCAhkEBCIIGEQAIJgUR6ns9ngCS1/4iTTjmfz91u15VKuSTOWyg2Pjqdzmq1CnOU+EhyOBwUSbATl48ks9lsPp+Hubx7SjIajZbLJSSCSMbj8Xa7hUQQiRoiURRBImt57/V6kAgieTwejUYjjmNIpJCoDAaD/X4PiSCS9Xqt9l2QpLfgKvV6nQMVQaNEpd/vH49HSASRLBaLyWQCiSCS6/XabrchsWqhsnP7ZrN5u90gMbRQ5T/mGA6Hu90OEjNJZdPadDp1cv7o61pSwdwVRZGTU3ovSapZS9Tb4mazgcSWpOx+ieNY7bhOpxMkUjbBaspydR7s5V+olD1x3e/3Vqt1uVxCIykbu9QfoVScfbsXkfbA0QWQEEggIZBAQiCBhEBCIIGEQAIJgQQSAgkkBBICCSQEEkgIJJAQSAgkkJA8+QJNGjsBrvuxHQAAAABJRU5ErkJggg==)
|
29296958 |
| 1403 | dbPTM | 36016369 | |
| 1403 | O-GlycoProteomDB | ||
| 1403 | PolarProtDb |
|
29296958 |
| 1403 | PhosphoSitePlus |
|
|
| 1446 | PhosphoSitePlus |
|
|
| 1446 | dbPTM | 37819195 | |
| 1446 | O-GlycoProteomDB |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Collagen |
| InterPro | Collagen_IV_NC |
| InterPro | Collagen_IV_NC_sf |
| InterPro | CTDL_fold |
| Pfam | C4 |
| Pfam | Collagen |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| CO4A1_HUMAN | 2 | 12011424 |
| ARMS2_HUMAN | 2 | 19696174 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.