Gene name
CD1D (CD1A)
Experiment(s)
For this entry:
CD1D_HUMAN (CD1D)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Rodionov DG,Nordeng TW,Pedersen K,Balk SP,Bakke O (1999) A critical tyrosine residue in the cytoplasmic tail is important for CD1d internalization but not for its basolateral sorting in MDCK cells., J Immunol, 162, 1488-95. [PubMed] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 19 | Signal peptide |
| 20 | 303 | Extracellular |
| 304 | 322 | Membrane |
| 323 | 335 | Cytoplasmic |
Phosphorylation
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Ig-like_dom |
| InterPro | Ig-like_dom_sf |
| InterPro | Ig-like_fold |
| InterPro | Ig_C1-set |
| InterPro | MHC_I-like_Ag-recog |
| InterPro | MHC_I-like_Ag-recog_sf |
| InterPro | MHC_I/II-like_Ag-recog |
| Pfam | C1-set |
| Pfam | MHC_I_3 |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| DLG1_HUMAN | 2 | 30126976 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.