Gene name
CPO
Experiment(s)
For this entry:
CBPO_HUMAN (CPO)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Lyons PJ,Fricker LD (2011) Carboxypeptidase O is a glycosylphosphatidylinositol-anchored intestinal peptidase with acidic amino acid specificity., J Biol Chem, 286, 39023-32. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes | Also detected in D. rerio (fish) enterocytes apically |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 374 | Extracellular |
Phosphorylation
Glycosylation
| Position | Site resource | Glycan resource | PubMed link(s) |
|---|---|---|---|
| 187 | N-GlycoSiteAtlas | 24191733 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Peptidase_M14 |
| Pfam | Peptidase_M14 |