Gene name
SERPINA6 (CBG)
Experiment(s)
For this entry:
CBG_HUMAN (SERPINA6)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Larsen JE,Avvakumov GV,Hammond GL,Vogel LK (1999) N-glycans are not the signal for apical sorting of corticosteroid binding globulin in MDCK cells., FEBS Lett, 451, 19-22. [PubMed] [DOI] |
| Evidence level | Selective medium analysis |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes | Absence of N-glycans do not affect polarized sorting |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 405 | Extracellular |
Phosphorylation
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Serpin_CS |
| InterPro | Serpin_dom |
| InterPro | Serpin_fam |
| InterPro | Serpin_sf |
| InterPro | Serpin_sf_1 |
| InterPro | Serpin_sf_2 |
| Pfam | Serpin |