Gene name
Ctsb (CPSB)
Experiment(s)
For this entry:
CATB_HUMAN (Ctsb)
| Species | Homo sapiens |
|---|---|
| Localization | Non polar membrane |
| Reference |
Touzelet O,Broadbent L,Armstrong SD,Aljabr W,Cloutman-Green E,Power UF,Hiscox JA (2020) The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins., Mol Cell Proteomics, 19, 793-807. [PubMed] [DOI] |
| Evidence level | Large-scale proteomics |
| Organ | Lung |
| Cell | Airway epithel cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 339 | Extracellular |
Phosphorylation
Glycosylation
| Position | Site resource | Glycan resource | PubMed link(s) |
|---|---|---|---|
| 38 | N-GlycoSiteAtlas | 24495048 | |
| 192 | dbPTM | 3463996 | |
| 192 | N-GlycoSiteAtlas | 24495048 | |
| 192 | UniProtKB | 3463996 | |
| 289 | N-GlycoSiteAtlas | 24495048 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Papain-like_cys_pep_sf |
| InterPro | Pept_asp_AS |
| InterPro | Pept_cys_AS |
| InterPro | Pept_his_AS |
| InterPro | Peptidase_C1A_C |
| InterPro | Propeptide_C1A |
| Pfam | Peptidase_C1 |
| Pfam | Propeptide_C1 |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| MLH1_HUMAN | 7 | 20706999 |
| POL_HV1B1 | 2 | 22190034 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.