Gene name
Cdh1 (CDHE,UVO)
Experiment(s)
For this entry:
CADH1_RAT (Cdh1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Gee HY,Jun I,Braun DA,Lawson JA,Halbritter J,Shril S,Nelson CP,Tan W,Stein D,Wassner AJ,Ferguson MA,Gucev Z,Sayer JA,Milosevic D,Baum M,Tasic V,Lee MG,Hildebrandt F (2016) Mutations in SLC26A1 Cause Nephrolithiasis., Am J Hum Genet, 98, 1228-1234. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 23 | Signal peptide |
| 24 | 714 | Extracellular |
| 715 | 734 | Membrane |
| 735 | 886 | Cytoplasmic |
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Cadherin |
| InterPro | Cadherin-like_dom |
| InterPro | Cadherin-like_sf |
| InterPro | Cadherin_CS |
| InterPro | Cadherin_cytoplasmic-dom |
| InterPro | Cadherin_pro_dom |
| InterPro | Catenin_binding_dom_sf |
| Pfam | Cadherin |
| Pfam | Cadherin_C |
| Pfam | Cadherin_pro |