Gene name
BST2 (Damp1)
Experiment(s)
For this entry:
BST2_HUMAN (BST2)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Rollason R,Korolchuk V,Hamilton C,Jepson M,Banting G (2009) A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells., J Cell Biol, 184, 721-36. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Large intestine |
| Cell | CACO-2 cells (enterocytes) |
| Notes | Apical localization depends on ARHGAP44 |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 21 | Cytoplasmic |
| 22 | 44 | Membrane |
| 45 | 166 | Extracellular |
| 167 | 181 | Membrane |
| 181 | 181 | Cytoplasmic |
Phosphorylation
Glycosylation
| Position | Site resource | Glycan resource | PubMed link(s) |
|---|---|---|---|
| 65 | Glyconnect |
|
29391424 |
| 65 | UniProtKB | 19159218 , 19349973 , 19737401 , 19879838 | |
| 65 | UniPep | ||
| 65 | PolarProtDb | 31844046 | |
| 65 | N-GlycoSiteAtlas | 24495048 | |
| 65 | dbPTM | 19159218 , 19349973 , 19737401 , 19879838 | |
| 65 | Glyconnect |
|
29741879 |
| 65 | Glyconnect |
|
29391424 |
| 65 | Glyconnect |
|
29391424 |
| 65 | Glyconnect |
|
29391424 |
| 65 | Glyconnect |
|
29391424 |
| 65 | Glyconnect |
|
29391424 |
| 65 | Glyconnect |
|
29391424 |
| 92 | UniProtKB | 19737401 , 19879838 | |
| 92 | Glyconnect |
|
29741879 |
| 92 | PolarProtDb |
|
29675740 |
| 92 | PolarProtDb |
|
29675740 |
| 92 | PolarProtDb |
|
29675740 |
| 92 | PolarProtDb |
|
29675740 |
| 92 | Glyconnect |
|
29741879 |
| 92 | dbPTM | 19737401 , 19879838 | |
| 92 | N-GlycoSiteAtlas | 24495048 | |
| 92 | PolarProtDb |
|
29675740 |
| 121 | O-GlycoProteomDB | ||
| 121 | dbPTM | 55831799 | |
| 121 | PhosphoSitePlus |
|
|
| 122 | O-GlycoProteomDB | ||
| 122 | dbPTM | 55831803 | |
| 122 | PhosphoSitePlus |
|
|
| 131 | O-GlycoProteomDB | ||
| 131 | dbPTM | 63752265 | |
| 131 | PhosphoSitePlus |
|
Family and domain data
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| VPU_HV1B1 | 7 | 22072710 |
| LIRA4_HUMAN | 2 | 19564354 |
| CD81_HUMAN | 3 | 32296183 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.