Gene name
SLC7A9 (Bat1)
Experiment(s)
For this entry:
BAT1_HUMAN (SLC7A9)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Mizoguchi K,Cha SH,Chairoungdua A,Kim DK,Shigeta Y,Matsuo H,Fukushima J,Awa Y,Akakura K,Goya T,Ito H,Endou H,Kanai Y (2001) Human cystinuria-related transporter: localization and functional characterization., Kidney Int, 59, 1821-33. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes | Covalently linked heterodimer with SLC3A1 |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 29 | Cytoplasmic |
| 30 | 50 | Membrane |
| 51 | 63 | Extracellular |
| 64 | 84 | Membrane |
| 85 | 109 | Cytoplasmic |
| 110 | 130 | Membrane |
| 131 | 149 | Extracellular |
| 150 | 170 | Membrane |
| 171 | 179 | Cytoplasmic |
| 180 | 200 | Membrane |
| 201 | 219 | Extracellular |
| 220 | 240 | Membrane |
| 241 | 253 | Cytoplasmic |
| 254 | 274 | Membrane |
| 275 | 301 | Extracellular |
| 302 | 322 | Membrane |
| 323 | 349 | Cytoplasmic |
| 350 | 369 | Membrane |
| 370 | 376 | Extracellular |
| 377 | 396 | Membrane |
| 397 | 409 | Cytoplasmic |
| 410 | 430 | Membrane |
| 431 | 436 | Extracellular |
| 437 | 456 | Membrane |
| 457 | 487 | Cytoplasmic |
Eukaryotic Linear Motif (ELM)
| Start | End | Sequence | Motif |
|---|---|---|---|
| 5 | 9 | GLRKR | TRG_ER_diArg_1 |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | AA/rel_permease1 |
| Pfam | AA_permease_2 |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| CREB3_HUMAN | 3 | 25910212 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.