Gene name
SLC22A13 (OCTL1,ORCTL3)
Experiment(s)
For this entry:
B2GV36_RAT (SLC22A13)
| Species | Rattus norvegicus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Bahn A,Hagos Y,Reuter S,Balen D,Brzica H,Krick W,Burckhardt BC,Sabolic I,Burckhardt G (2008) Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13)., J Biol Chem, 283, 16332-41. [PubMed] [DOI] |
| Evidence level | Membrane preparation |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes | Expression was gender-dependent |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 19 | Cytoplasmic |
| 20 | 39 | Membrane |
| 40 | 138 | Extracellular |
| 139 | 159 | Membrane |
| 160 | 166 | Cytoplasmic |
| 167 | 186 | Membrane |
| 187 | 193 | Extracellular |
| 194 | 214 | Membrane |
| 215 | 224 | Cytoplasmic |
| 225 | 246 | Membrane |
| 247 | 251 | Extracellular |
| 252 | 271 | Membrane |
| 272 | 332 | Cytoplasmic |
| 333 | 352 | Membrane |
| 353 | 362 | Extracellular |
| 363 | 383 | Membrane |
| 384 | 390 | Cytoplasmic |
| 391 | 411 | Membrane |
| 412 | 418 | Extracellular |
| 419 | 439 | Membrane |
| 440 | 451 | Cytoplasmic |
| 452 | 472 | Membrane |
| 473 | 478 | Extracellular |
| 479 | 499 | Membrane |
| 500 | 551 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | MFS_dom |
| InterPro | MFS_sugar_transport-like |
| InterPro | MFS_trans_sf |
| InterPro | Sugar_transporter_CS |
| Pfam | Sugar_tr |