Gene name

Atp1b1 (ATP1B,Atp4b)

Experiment(s)

For this entry:
AT1B1_HUMAN (Atp1b1)
Species Homo sapiens
Localization Basolateral plasma membrane
Reference Lobato-Álvarez JA,Roldán ML,López-Murillo TD,González-Ramírez R,Bonilla-Delgado J,Shoshani L (2016) The Apical Localization of Na<sup>+</sup>, K<sup>+</sup>-ATPase in Cultured Human Retinal Pigment Epithelial Cells Depends on Expression of the β<sub>2</sub> Subunit., Front Physiol, 7, 450.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Retina
Cell ARPE-19 cells (pigment epithel cells)
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 32 Cytoplasmic
33 53 Membrane
54 303 Extracellular
Phosphorylation
Position Resource
101 3413489
229 55369659
235 55369664
254 23084875
285 55369669
Glycosylation

Family and domain data

Database Domain/Family name
InterPro Na/K_ATPase_sub_beta
InterPro Na/K_ATPase_sub_beta_chordates
InterPro Na/K_ATPase_sub_beta_sf
Pfam Na_K-ATPase

Interactions

With (links to EBI) #Exp PubMed links
AT1A1_HUMAN 2 30021884 , 25012180
KIRR3_HUMAN 4 25902260
ESR1_HUMAN 2 31527615
P2RY6_HUMAN 3 30833792
B3AT_HUMAN 8 25012180
Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.

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