Gene name
Amn
Experiment(s)
For this entry:
AMNLS_HUMAN (Amn)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Fyfe JC,Madsen M,Højrup P,Christensen EI,Tanner SM,de la Chapelle A,He Q,Moestrup SK (2004) The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless., Blood, 103, 1573-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 20 | Signal peptide |
| 21 | 361 | Extracellular |
| 362 | 383 | Membrane |
| 384 | 453 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | AMN |
| Pfam | Amnionless |