Gene name
ADAM17 (TACE,CSVP)
Experiment(s)
For this entry:
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 17 | Signal peptide |
| 18 | 671 | Extracellular |
| 672 | 691 | Membrane |
| 692 | 824 | Cytoplasmic |
Phosphorylation
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | ADAM10_ADAM17 |
| InterPro | ADAM17_MPD |
| InterPro | Disintegrin_dom |
| InterPro | Disintegrin_dom_sf |
| InterPro | MetalloPept_cat_dom_sf |
| InterPro | Peptidase_M12B |
| InterPro | Peptidase_M12B_N |
| Pfam | ADAM17_MPD |
| Pfam | Disintegrin |
| Pfam | Pep_M12B_propep |