Gene name

ADAM17 (TACE,CSVP)

Experiment(s)

For this entry:
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 17 Signal peptide
18 671 Extracellular
672 691 Membrane
692 824 Cytoplasmic
Phosphorylation
Glycosylation

Family and domain data

Database Domain/Family name
InterPro ADAM10_ADAM17
InterPro ADAM17_MPD
InterPro Disintegrin_dom
InterPro Disintegrin_dom_sf
InterPro MetalloPept_cat_dom_sf
InterPro Peptidase_M12B
InterPro Peptidase_M12B_N
Pfam ADAM17_MPD
Pfam Disintegrin
Pfam Pep_M12B_propep

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