Gene name
ADORA2B
Experiment(s)
For this entry:
AA2BR_MOUSE (ADORA2B)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Battistone MA,Merkulova M,Park YJ,Peralta MA,Gombar F,Brown D,Breton S (2019) Unravelling purinergic regulation in the epididymis: activation of V-ATPase-dependent acidification by luminal ATP and adenosine., J Physiol, 597, 1957-1973. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Epididymis |
| Cell | Principal cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 9 | Extracellular |
| 10 | 31 | Membrane |
| 32 | 44 | Cytoplasmic |
| 45 | 65 | Membrane |
| 66 | 79 | Extracellular |
| 80 | 101 | Membrane |
| 102 | 122 | Cytoplasmic |
| 123 | 144 | Membrane |
| 145 | 180 | Extracellular |
| 181 | 201 | Membrane |
| 202 | 235 | Cytoplasmic |
| 236 | 256 | Membrane |
| 257 | 271 | Extracellular |
| 272 | 292 | Membrane |
| 293 | 332 | Cytoplasmic |
Phosphorylation
| Position | Resource |
|---|---|
| 113 | 459413 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Adeno_A2B_rcpt |
| InterPro | Adenosn_rcpt |
| InterPro | GPCR_Rhodpsn |
| InterPro | GPCR_Rhodpsn_7TM |
| Pfam | 7tm_1 |