Gene name
STEAP3 (TSAP6)
Experiment(s)
For this entry:
A0A5F4C7U1_CANLF (STEAP3)
| Species | Canis lupus familiaris |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Caceres PS,Gravotta D,Zager PJ,Dephoure N,Rodriguez-Boulan E (2019) Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins., Proc Natl Acad Sci U S A, 116, 11796-11805. [PubMed] [DOI] |
| Evidence level | Large-scale proteomics |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes | The N-terminus of the dog protein is incorrectly extened in UniProt |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 283 | Cytoplasmic |
| 284 | 302 | Membrane |
| 303 | 328 | Extracellular |
| 329 | 350 | Membrane |
| 351 | 374 | Cytoplasmic |
| 375 | 393 | Membrane |
| 394 | 428 | Extracellular |
| 429 | 447 | Membrane |
| 448 | 463 | Cytoplasmic |
| 464 | 482 | Membrane |
| 483 | 502 | Extracellular |
| 503 | 524 | Membrane |
| 525 | 558 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Fe3_Rdtase_TM_dom |
| InterPro | NAD(P)-bd_dom_sf |
| InterPro | P5C_Rdtase_cat_N |
| Pfam | F420_oxidored |
| Pfam | Ferric_reduct |