Gene name
Aqp8
Experiment(s)
For this entry:
A0A0X1KG59_MOUSE (Aqp8)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Calamita G,Ferri D,Bazzini C,Mazzone A,Bottà G,Liquori GE,Paulmichl M,Portincasa P,Meyer G,Svelto M (2005) Expression and subcellular localization of the AQP8 and AQP1 water channels in the mouse gall-bladder epithelium., Biol Cell, 97, 415-23. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Gall bladder |
| Cell | Epithelial cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Loading data
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 36 | Cytoplasmic |
| 37 | 54 | Membrane |
| 55 | 65 | Extracellular |
| 66 | 83 | Membrane |
| 84 | 86 | Cytoplasmic |
| 87 | 100 | Re-entrant loop |
| 101 | 109 | Cytoplasmic |
| 110 | 127 | Membrane |
| 128 | 156 | Extracellular |
| 157 | 174 | Membrane |
| 175 | 183 | Cytoplasmic |
| 184 | 201 | Membrane |
| 202 | 205 | Extracellular |
| 206 | 219 | Re-entrant loop |
| 220 | 226 | Extracellular |
| 227 | 244 | Membrane |
| 245 | 260 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Aquaporin-like |
| InterPro | Aquaporin_8 |
| InterPro | Aquaporin_transptr |
| InterPro | MIP |
| InterPro | MIP_CS |
| Pfam | MIP |