Gene name

TFRC (Trfr,Tfrc)

Experiment(s)

For this entry:
TFR1_RAT (TFRC)
Species Rattus norvegicus
Localization Basolateral plasma membrane
Reference Sugasawa K,Deguchi J,Okami T,Yamamoto A,Omori K,Uyama M,Tashiro Y (1994) Immunocytochemical analyses of distributions of Na, K-ATPase and GLUT1, insulin and transferrin receptors in the developing retinal pigment epithelial cells., Cell Struct Funct, 19, 21-8.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Retina
Cell Pigment epithel cells
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 65 Cytoplasmic
66 86 Membrane
87 761 Extracellular

Family and domain data

Database Domain/Family name
InterPro PA_domain
InterPro Peptidase_M28
InterPro Peptidase_M28B
InterPro TfR
InterPro TFR-like_dimer_dom
InterPro TFR-like_dimer_dom_sf
InterPro TfR1/2_PA
Pfam PA
Pfam Peptidase_M28
Pfam TFR_dimer

Interactions

With (links to EBI) #Exp PubMed links
INSR_RAT 2 30300385
Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.

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