Gene name
SLCO4C1 (OATP4C1,SLC21A20,OATPX)
Experiment(s)
For this entry:
SO4C1_RAT (SLCO4C1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Mikkaichi T,Suzuki T,Onogawa T,Tanemoto M,Mizutamari H,Okada M,Chaki T,Masuda S,Tokui T,Eto N,Abe M,Satoh F,Unno M,Hishinuma T,Inui K,Ito S,Goto J,Abe T (2004) Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney., Proc Natl Acad Sci U S A, 101, 3569-74. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 105 | Cytoplasmic |
| 106 | 126 | Membrane |
| 127 | 142 | Extracellular |
| 143 | 165 | Membrane |
| 166 | 173 | Cytoplasmic |
| 174 | 195 | Membrane |
| 196 | 228 | Extracellular |
| 229 | 250 | Membrane |
| 251 | 266 | Cytoplasmic |
| 267 | 289 | Membrane |
| 290 | 312 | Extracellular |
| 313 | 334 | Membrane |
| 335 | 381 | Cytoplasmic |
| 382 | 403 | Membrane |
| 404 | 419 | Extracellular |
| 420 | 443 | Membrane |
| 444 | 455 | Cytoplasmic |
| 456 | 474 | Membrane |
| 475 | 578 | Extracellular |
| 579 | 602 | Membrane |
| 603 | 614 | Cytoplasmic |
| 615 | 638 | Membrane |
| 639 | 666 | Extracellular |
| 667 | 690 | Membrane |
| 691 | 723 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Kazal_dom |
| InterPro | Kazal_dom_sf |
| InterPro | MFS_dom |
| InterPro | MFS_trans_sf |
| InterPro | OATP |
| Pfam | Kazal_2 |
| Pfam | OATP |