Gene name
SLC11A2 (Dct1,Dmt1,Nramp2)
Experiment(s)
For this entry:
NRAM2_RAT (SLC11A2)
| Species | Rattus norvegicus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Núñez MT,Tapia V,Rojas A,Aguirre P,Gómez F,Nualart F (2010) Iron supply determines apical/basolateral membrane distribution of intestinal iron transporters DMT1 and ferroportin 1., Am J Physiol Cell Physiol, 298, C477-85. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes | Localization is dynamic |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 66 | Cytoplasmic |
| 67 | 82 | Membrane |
| 83 | 106 | Extracellular |
| 107 | 123 | Membrane |
| 124 | 144 | Cytoplasmic |
| 145 | 169 | Membrane |
| 170 | 182 | Extracellular |
| 183 | 199 | Membrane |
| 200 | 201 | Cytoplasmic |
| 202 | 218 | Membrane |
| 219 | 256 | Extracellular |
| 257 | 273 | Membrane |
| 274 | 294 | Cytoplasmic |
| 295 | 311 | Membrane |
| 312 | 376 | Extracellular |
| 377 | 398 | Membrane |
| 399 | 408 | Cytoplasmic |
| 409 | 425 | Membrane |
| 426 | 439 | Extracellular |
| 440 | 461 | Membrane |
| 462 | 468 | Cytoplasmic |
| 469 | 490 | Membrane |
| 491 | 505 | Extracellular |
| 506 | 527 | Membrane |
| 528 | 568 | Cytoplasmic |