Gene name

Scgb1a1 (Ugb,UGL,Cc10,CCSP,Utg)

Experiment(s)

For this entry:
UTER_HUMAN (Scgb1a1)
Species Homo sapiens
Localization Apical plasma membrane
Reference Touzelet O,Broadbent L,Armstrong SD,Aljabr W,Cloutman-Green E,Power UF,Hiscox JA (2020) The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins., Mol Cell Proteomics, 19, 793-807.
[PubMed] [DOI]
Evidence level Large-scale proteomics
Organ Lung
Cell Airway epithel cells
Notes Only mock-transfected cells were considered
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 91 Extracellular
Phosphorylation
Position Resource
6 13309984

Family and domain data

Database Domain/Family name
InterPro Secretoglobin
InterPro Secretoglobin_1C-like
InterPro Secretoglobin_sf
InterPro Uteroglobin
Pfam Uteroglobin

Interactions

With (links to EBI) #Exp PubMed links
AQP6_HUMAN 3 32296183
TMM43_HUMAN 3 32296183
TRI32_HUMAN 7 25416956 , 31515488 , 32296183
Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.

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