Gene name
Slco1a1 (Oatp1,Oatp1a1,Slc21a1)
Experiment(s)
For this entry:
SO1A1_RAT (Slco1a1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Bergwerk AJ,Shi X,Ford AC,Kanai N,Jacquemin E,Burk RD,Bai S,Novikoff PM,Stieger B,Meier PJ,Schuster VL,Wolkoff AW (1996) Immunologic distribution of an organic anion transport protein in rat liver and kidney., Am J Physiol, 271, G231-8. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Liver |
| Cell | Hepatocytes |
| Notes |
SO1A1_RAT (Slco1a1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Bergwerk AJ,Shi X,Ford AC,Kanai N,Jacquemin E,Burk RD,Bai S,Novikoff PM,Stieger B,Meier PJ,Schuster VL,Wolkoff AW (1996) Immunologic distribution of an organic anion transport protein in rat liver and kidney., Am J Physiol, 271, G231-8. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
SO1A1_RAT (Slco1a1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Angeletti RH,Novikoff PM,Juvvadi SR,Fritschy JM,Meier PJ,Wolkoff AW (1997) The choroid plexus epithelium is the site of the organic anion transport protein in the brain., Proc Natl Acad Sci U S A, 94, 283-6. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Choroid plexus |
| Cell | Ependymal cells |
| Notes |
SO1A1_RAT (Slco1a1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Eckhardt U,Schroeder A,Stieger B,Höchli M,Landmann L,Tynes R,Meier PJ,Hagenbuch B (1999) Polyspecific substrate uptake by the hepatic organic anion transporter Oatp1 in stably transfected CHO cells., Am J Physiol, 276, G1037-42. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Liver |
| Cell | Hepatocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 20 | Cytoplasmic |
| 21 | 41 | Membrane |
| 42 | 57 | Extracellular |
| 58 | 79 | Membrane |
| 80 | 87 | Cytoplasmic |
| 88 | 109 | Membrane |
| 110 | 158 | Extracellular |
| 159 | 180 | Membrane |
| 181 | 195 | Cytoplasmic |
| 196 | 217 | Membrane |
| 218 | 243 | Extracellular |
| 244 | 265 | Membrane |
| 266 | 315 | Cytoplasmic |
| 316 | 337 | Membrane |
| 338 | 353 | Extracellular |
| 354 | 376 | Membrane |
| 377 | 386 | Cytoplasmic |
| 387 | 408 | Membrane |
| 409 | 512 | Extracellular |
| 513 | 535 | Membrane |
| 536 | 548 | Cytoplasmic |
| 549 | 571 | Membrane |
| 572 | 600 | Extracellular |
| 601 | 622 | Membrane |
| 623 | 670 | Cytoplasmic |
Eukaryotic Linear Motif (ELM)
| Start | End | Sequence | Motif |
|---|---|---|---|
| 666 | 670 | LKTKL | TRG_PTS1 |
Phosphorylation
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Kazal_dom |
| InterPro | Kazal_dom_sf |
| InterPro | MFS_dom |
| InterPro | MFS_trans_sf |
| InterPro | OATP |
| Pfam | Kazal_2 |
| Pfam | OATP |