Gene name

SLC9A1 (NHE1,APNH1)

Experiment(s)

For this entry:
SL9A1_RAT (SLC9A1)
Species Rattus norvegicus
Localization Basolateral plasma membrane
Reference Nejsum LN,Praetorius J,Nielsen S (2005) NKCC1 and NHE1 are abundantly expressed in the basolateral plasma membrane of secretory coil cells in rat, mouse, and human sweat glands., Am J Physiol Cell Physiol, 289, C333-40.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Sweat glands
Cell Secretory cells
Notes
SL9A1_RAT (SLC9A1)
Species Rattus norvegicus
Localization Basolateral plasma membrane
Reference Nejsum LN,Praetorius J,Nielsen S (2005) NKCC1 and NHE1 are abundantly expressed in the basolateral plasma membrane of secretory coil cells in rat, mouse, and human sweat glands., Am J Physiol Cell Physiol, 289, C333-40.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Kidney
Cell Collecting ducts
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 15 Cytoplasmic
16 33 Membrane
34 107 Extracellular
108 126 Membrane
127 135 Cytoplasmic
136 153 Membrane
154 163 Extracellular
164 183 Membrane
184 192 Cytoplasmic
193 212 Membrane
213 228 Extracellular
229 249 Membrane
250 258 Cytoplasmic
259 277 Membrane
278 296 Extracellular
297 322 Membrane
323 331 Cytoplasmic
332 348 Membrane
349 350 Extracellular
351 371 Membrane
372 388 Cytoplasmic
389 407 Membrane
408 416 Extracellular
417 438 Membrane
439 454 Cytoplasmic
455 473 Membrane
474 482 Extracellular
483 503 Membrane
504 820 Cytoplasmic
Phosphorylation

Family and domain data

Database Domain/Family name
InterPro Cation/H_exchanger
InterPro Cation/H_exchanger_CPA1
InterPro Na/H_exchanger_1
InterPro NaH_exchanger
InterPro NHE_CaM-bd
Pfam Na_H_Exchanger
Pfam NEXCaM_BD

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