Gene name

SCNN1G

Experiment(s)

For this entry:
SCNNG_HUMAN (SCNN1G)
Species Homo sapiens
Localization Apical plasma membrane
Reference Hanukoglu I,Boggula VR,Vaknine H,Sharma S,Kleyman T,Hanukoglu A (2017) Expression of epithelial sodium channel (ENaC) and CFTR in the human epidermis and epidermal appendages., Histochem Cell Biol, 147, 733-748.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Sweat glands
Cell Ductal cells
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 53 Cytoplasmic
54 75 Membrane
76 536 Extracellular
537 558 Membrane
559 649 Cytoplasmic
Phosphorylation

Family and domain data

Database Domain/Family name
InterPro ENaC
InterPro ENaC_chordates
InterPro ENaC_CS
Pfam ASC

Interactions

With (links to EBI) #Exp PubMed links
SCNNA_HUMAN 3 21775436 , 16423824
Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.

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