Gene name
SLC47A1 (MATE1)
Experiment(s)
For this entry:
S47A1_HUMAN (SLC47A1)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Masuda S,Terada T,Yonezawa A,Tanihara Y,Kishimoto K,Katsura T,Ogawa O,Inui K (2006) Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2., J Am Soc Nephrol, 17, 2127-35. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
S47A1_HUMAN (SLC47A1)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Motohashi H,Nakao Y,Masuda S,Katsura T,Kamba T,Ogawa O,Inui K (2013) Precise comparison of protein localization among OCT, OAT, and MATE in human kidney., J Pharm Sci, 102, 3302-8. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 41 | Cytoplasmic |
| 42 | 61 | Membrane |
| 62 | 79 | Extracellular |
| 80 | 99 | Membrane |
| 100 | 117 | Cytoplasmic |
| 118 | 137 | Membrane |
| 138 | 157 | Extracellular |
| 158 | 177 | Membrane |
| 178 | 184 | Cytoplasmic |
| 185 | 204 | Membrane |
| 205 | 216 | Extracellular |
| 217 | 236 | Membrane |
| 237 | 256 | Cytoplasmic |
| 257 | 281 | Membrane |
| 282 | 295 | Extracellular |
| 296 | 315 | Membrane |
| 316 | 342 | Cytoplasmic |
| 343 | 362 | Membrane |
| 363 | 376 | Extracellular |
| 377 | 398 | Membrane |
| 399 | 406 | Cytoplasmic |
| 407 | 427 | Membrane |
| 428 | 434 | Extracellular |
| 435 | 454 | Membrane |
| 455 | 547 | Cytoplasmic |
| 548 | 567 | Membrane |
| 568 | 570 | Extracellular |
Family and domain data
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| FXYD6_HUMAN | 3 | 32296183 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.