Gene name
SLC41A1 (RAB29)
Experiment(s)
For this entry:
S41A1_MOUSE (SLC41A1)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Arjona FJ,Latta F,Mohammed SG,Thomassen M,van Wijk E,Bindels RJM,Hoenderop JGJ,de Baaij JHF (2019) SLC41A1 is essential for magnesium homeostasis in vivo., Pflugers Arch, 471, 845-860. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes | An HA tag was used for labelling |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 97 | Extracellular |
| 98 | 119 | Membrane |
| 120 | 180 | Cytoplasmic |
| 181 | 202 | Membrane |
| 203 | 213 | Extracellular |
| 214 | 240 | Membrane |
| 241 | 251 | Cytoplasmic |
| 252 | 273 | Membrane |
| 274 | 284 | Extracellular |
| 285 | 305 | Membrane |
| 306 | 314 | Cytoplasmic |
| 315 | 336 | Membrane |
| 337 | 407 | Extracellular |
| 408 | 428 | Membrane |
| 429 | 437 | Cytoplasmic |
| 438 | 459 | Membrane |
| 460 | 480 | Extracellular |
| 481 | 502 | Membrane |
| 503 | 512 | Cytoplasmic |
Phosphorylation
| Position | Resource |
|---|---|
| 72 | 36128532 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | SLC41_membr_dom |
| InterPro | SLC41_membr_dom_sf |
| Pfam | MgtE |