Gene name
Slc39a1 (IRT1,Zip1,Zirtl)
Experiment(s)
For this entry:
S39A1_HUMAN (Slc39a1)
| Species | Homo sapiens |
|---|---|
| Localization | Non polar membrane |
| Reference |
Desouki MM,Geradts J,Milon B,Franklin RB,Costello LC (2007) hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands., Mol Cancer, 6, 37. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Prostate |
| Cell | Epithelial cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 30 | Extracellular |
| 31 | 51 | Membrane |
| 52 | 68 | Cytoplasmic |
| 69 | 89 | Membrane |
| 90 | 110 | Extracellular |
| 111 | 131 | Membrane |
| 132 | 179 | Cytoplasmic |
| 180 | 199 | Membrane |
| 200 | 209 | Extracellular |
| 210 | 230 | Membrane |
| 231 | 239 | Cytoplasmic |
| 240 | 260 | Membrane |
| 261 | 272 | Extracellular |
| 273 | 292 | Membrane |
| 293 | 302 | Cytoplasmic |
| 303 | 322 | Membrane |
| 323 | 324 | Extracellular |
Family and domain data
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| COMT_HUMAN | 3 | 32296183 |
| CXCL9_HUMAN | 3 | 32296183 |
| TMM60_HUMAN | 3 | 32296183 |
| YIPF6_HUMAN | 3 | 32296183 |
| A5PKU2_HUMAN | 3 | 32296183 |
| CY561_HUMAN | 3 | 32296183 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.