Gene name
Slc36a2 (Pat2,Tramd1)
Experiment(s)
For this entry:
S36A2_HUMAN (Slc36a2)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Bröer S,Bailey CG,Kowalczuk S,Ng C,Vanslambrouck JM,Rodgers H,Auray-Blais C,Cavanaugh JA,Bröer A,Rasko JE (2008) Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters., J Clin Invest, 118, 3881-92. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 58 | Cytoplasmic |
| 59 | 79 | Membrane |
| 80 | 84 | Extracellular |
| 85 | 106 | Membrane |
| 107 | 148 | Cytoplasmic |
| 149 | 169 | Membrane |
| 170 | 197 | Extracellular |
| 198 | 218 | Membrane |
| 219 | 225 | Cytoplasmic |
| 226 | 247 | Membrane |
| 248 | 264 | Extracellular |
| 265 | 285 | Membrane |
| 286 | 297 | Cytoplasmic |
| 298 | 319 | Membrane |
| 320 | 340 | Extracellular |
| 341 | 361 | Membrane |
| 362 | 382 | Cytoplasmic |
| 383 | 400 | Membrane |
| 401 | 405 | Extracellular |
| 406 | 426 | Membrane |
| 427 | 440 | Cytoplasmic |
| 441 | 462 | Membrane |
| 463 | 483 | Extracellular |
Phosphorylation
Glycosylation
| Position | Site resource | Glycan resource | PubMed link(s) |
|---|---|---|---|
| 181 | N-GlycoSiteAtlas |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | AA_transpt_TM |
| Pfam | Aa_trans |