Gene name
Slc26a1 (Sat1)
Experiment(s)
For this entry:
S26A1_RAT (Slc26a1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Gee HY,Jun I,Braun DA,Lawson JA,Halbritter J,Shril S,Nelson CP,Tan W,Stein D,Wassner AJ,Ferguson MA,Gucev Z,Sayer JA,Milosevic D,Baum M,Tasic V,Lee MG,Hildebrandt F (2016) Mutations in SLC26A1 Cause Nephrolithiasis., Am J Hum Genet, 98, 1228-1234. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
S26A1_RAT (Slc26a1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Non polar membrane |
| Reference |
Gee HY,Jun I,Braun DA,Lawson JA,Halbritter J,Shril S,Nelson CP,Tan W,Stein D,Wassner AJ,Ferguson MA,Gucev Z,Sayer JA,Milosevic D,Baum M,Tasic V,Lee MG,Hildebrandt F (2016) Mutations in SLC26A1 Cause Nephrolithiasis., Am J Hum Genet, 98, 1228-1234. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 72 | Cytoplasmic |
| 73 | 93 | Membrane |
| 94 | 98 | Extracellular |
| 99 | 118 | Membrane |
| 119 | 120 | Cytoplasmic |
| 121 | 140 | Membrane |
| 141 | 181 | Extracellular |
| 182 | 202 | Membrane |
| 203 | 214 | Cytoplasmic |
| 215 | 232 | Membrane |
| 233 | 262 | Extracellular |
| 263 | 280 | Membrane |
| 281 | 293 | Cytoplasmic |
| 294 | 313 | Membrane |
| 314 | 343 | Extracellular |
| 344 | 364 | Membrane |
| 365 | 380 | Cytoplasmic |
| 381 | 401 | Membrane |
| 402 | 417 | Extracellular |
| 418 | 438 | Membrane |
| 439 | 440 | Cytoplasmic |
| 441 | 459 | Membrane |
| 460 | 475 | Extracellular |
| 476 | 503 | Membrane |
| 504 | 703 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | S04_transporter_CS |
| InterPro | SLC26A/SulP_dom |
| InterPro | SLC26A/SulP_fam |
| InterPro | SLC26A1 |
| InterPro | STAS_dom |
| InterPro | STAS_dom_sf |
| Pfam | STAS |
| Pfam | Sulfate_transp |