Gene name

UPK1A (TSPAN21)

Experiment(s)

For this entry:
Q06AT5_PIG (UPK1A)
Species Sus scrofa
Localization Apical plasma membrane
Reference Višnjar T,Chesi G,Iacobacci S,Polishchuk E,Resnik N,Robenek H,Kreft M,Romih R,Polishchuk R,Kreft ME (2017) Uroplakin traffic through the Golgi apparatus induces its fragmentation: new insights from novel in vitro models., Sci Rep, 7, 12842.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Bladder
Cell Urothelial cells
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 14 Cytoplasmic
15 38 Membrane
39 59 Extracellular
60 82 Membrane
83 90 Cytoplasmic
91 113 Membrane
114 231 Extracellular
232 253 Membrane
254 257 Cytoplasmic

Family and domain data

Database Domain/Family name
InterPro Tetraspanin
InterPro Tetraspanin/Peripherin
InterPro Tetraspanin_EC2_sf
InterPro Uroplakin-1a
Pfam Tetraspanin

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