Gene name

Prom1 (PROML1)

Experiment(s)

For this entry:
PROM1_HUMAN (Prom1)
Species Homo sapiens
Localization Apical plasma membrane
Reference Karbanová J,Missol-Kolka E,Fonseca AV,Lorra C,Janich P,Hollerová H,Jászai J,Ehrmann J,Kolár Z,Liebers C,Arl S,Subrtová D,Freund D,Mokry J,Huttner WB,Corbeil D (2008) The stem cell marker CD133 (Prominin-1) is expressed in various human glandular epithelia., J Histochem Cytochem, 56, 977-93.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Lacrimal gland
Cell Secretory cells
Notes
PROM1_HUMAN (Prom1)
Species Homo sapiens
Localization Apical plasma membrane
Reference Karbanová J,Missol-Kolka E,Fonseca AV,Lorra C,Janich P,Hollerová H,Jászai J,Ehrmann J,Kolár Z,Liebers C,Arl S,Subrtová D,Freund D,Mokry J,Huttner WB,Corbeil D (2008) The stem cell marker CD133 (Prominin-1) is expressed in various human glandular epithelia., J Histochem Cytochem, 56, 977-93.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Liver
Cell Bile duct cells
Notes
PROM1_HUMAN (Prom1)
Species Homo sapiens
Localization Apical plasma membrane
Reference Karbanová J,Missol-Kolka E,Fonseca AV,Lorra C,Janich P,Hollerová H,Jászai J,Ehrmann J,Kolár Z,Liebers C,Arl S,Subrtová D,Freund D,Mokry J,Huttner WB,Corbeil D (2008) The stem cell marker CD133 (Prominin-1) is expressed in various human glandular epithelia., J Histochem Cytochem, 56, 977-93.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Salivary gland
Cell Ductal cells
Notes
PROM1_HUMAN (Prom1)
Species Homo sapiens
Localization Apical plasma membrane
Reference Karbanová J,Missol-Kolka E,Fonseca AV,Lorra C,Janich P,Hollerová H,Jászai J,Ehrmann J,Kolár Z,Liebers C,Arl S,Subrtová D,Freund D,Mokry J,Huttner WB,Corbeil D (2008) The stem cell marker CD133 (Prominin-1) is expressed in various human glandular epithelia., J Histochem Cytochem, 56, 977-93.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Sweat glands
Cell Secretory cells
Notes
PROM1_HUMAN (Prom1)
Species Homo sapiens
Localization Apical plasma membrane
Reference Karbanová J,Missol-Kolka E,Fonseca AV,Lorra C,Janich P,Hollerová H,Jászai J,Ehrmann J,Kolár Z,Liebers C,Arl S,Subrtová D,Freund D,Mokry J,Huttner WB,Corbeil D (2008) The stem cell marker CD133 (Prominin-1) is expressed in various human glandular epithelia., J Histochem Cytochem, 56, 977-93.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Uterus
Cell Endometrial cells
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 20 Signal peptide
21 106 Extracellular
107 132 Membrane
133 156 Cytoplasmic
157 177 Membrane
178 435 Extracellular
436 461 Membrane
462 481 Cytoplasmic
482 507 Membrane
508 792 Extracellular
793 813 Membrane
814 865 Cytoplasmic
Phosphorylation
Glycosylation

Family and domain data

Database Domain/Family name
InterPro Prominin
Pfam Prominin

Interactions

With (links to EBI) #Exp PubMed links
CTNB1_HUMAN 3 23084749
HDAC6_HUMAN 4 23084749
Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.

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