Gene name

Serpinf1 (Pedf,Sdf3,Dmrs91)

Experiment(s)

For this entry:
PEDF_HUMAN (Serpinf1)
Species Homo sapiens
Localization Non polar membrane
Reference Touzelet O,Broadbent L,Armstrong SD,Aljabr W,Cloutman-Green E,Power UF,Hiscox JA (2020) The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins., Mol Cell Proteomics, 19, 793-807.
[PubMed] [DOI]
Evidence level Large-scale proteomics
Organ Lung
Cell Airway epithel cells
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 418 Extracellular
Phosphorylation
Glycosylation

Family and domain data

Database Domain/Family name
InterPro PEDF
InterPro Serpin_CS
InterPro Serpin_dom
InterPro Serpin_fam
InterPro Serpin_sf
InterPro Serpin_sf_1
InterPro Serpin_sf_2
Pfam Serpin

Interactions

With (links to EBI) #Exp PubMed links
SGTB_HUMAN 3 32296183
MLH1_HUMAN 2 20706999
IMPCT_HUMAN 3 32296183
EPMIP_HUMAN 11 25416956 , 25910212 , 32296183
Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.

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