Gene name
OTOA
Experiment(s)
For this entry:
OTOAN_MOUSE (OTOA)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Zwaenepoel I,Mustapha M,Leibovici M,Verpy E,Goodyear R,Liu XZ,Nouaille S,Nance WE,Kanaan M,Avraham KB,Tekaia F,Loiselet J,Lathrop M,Richardson G,Petit C (2002) Otoancorin, an inner ear protein restricted to the interface between the apical surface of sensory epithelia and their overlying acellular gels, is defective in autosomal recessive deafness DFNB22., Proc Natl Acad Sci U S A, 99, 6240-5. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Inner ear |
| Cell | Hair cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 1137 | Extracellular |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Otoancorin |
| InterPro | Stereocilin-rel |