Gene name

MET

Experiment(s)

For this entry:
MET_CANLF (MET)
Species Canis lupus familiaris
Localization Basolateral plasma membrane
Reference Caceres PS,Gravotta D,Zager PJ,Dephoure N,Rodriguez-Boulan E (2019) Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins., Proc Natl Acad Sci U S A, 116, 11796-11805.
[PubMed] [DOI]
Evidence level Large-scale proteomics
Organ Kidney
Cell MDCK cells (distal tubule)
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 24 Signal peptide
25 933 Extracellular
934 954 Membrane
955 1382 Cytoplasmic

Family and domain data

Database Domain/Family name
InterPro Ig-like_fold
InterPro Ig_E-set
InterPro IPT_dom
InterPro Kinase-like_dom_sf
InterPro Plexin
InterPro Plexin_repeat
InterPro Prot_kinase_dom
InterPro Protein_kinase_ATP_BS
InterPro PSI
InterPro Semap_dom
InterPro Semap_dom_sf
InterPro Ser-Thr/Tyr_kinase_cat_dom
InterPro Tyr_kinase_AS
InterPro Tyr_kinase_cat_dom
InterPro Tyr_kinase_HGF/MSP_rcpt
InterPro WD40/YVTN_repeat-like_dom_sf
Pfam PK_Tyr_Ser-Thr
Pfam PSI
Pfam Sema
Pfam TIG

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