Gene name

Slc2a5 (Glut5)

Experiment(s)

For this entry:
GTR5_RAT (Slc2a5)
Species Rattus norvegicus
Localization Apical plasma membrane
Reference Inukai K,Shewan AM,Pascoe WS,Katayama S,James DE,Oka Y (2004) Carboxy terminus of glucose transporter 3 contains an apical membrane targeting domain., Mol Endocrinol, 18, 339-49.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Kidney
Cell MDCK cells (distal tubule)
Notes
GTR5_RAT (Slc2a5)
Species Rattus norvegicus
Localization Apical plasma membrane
Reference Inukai K,Takata K,Asano T,Katagiri H,Ishihara H,Nakazaki M,Fukushima Y,Yazaki Y,Kikuchi M,Oka Y (1997) Targeting of GLUT1-GLUT5 chimeric proteins in the polarized cell line Caco-2., Mol Endocrinol, 11, 442-9.
[PubMed] [DOI]
Evidence level Antibody staining + sub-protein manipulation
Organ Large intestine
Cell CACO-2 cells (enterocytes)
Notes The large intracellular loop was identified as a determinat of sorting
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 18 Cytoplasmic
19 40 Membrane
41 70 Extracellular
71 91 Membrane
92 98 Cytoplasmic
99 118 Membrane
119 125 Extracellular
126 146 Membrane
147 160 Cytoplasmic
161 180 Membrane
181 192 Extracellular
193 212 Membrane
213 277 Cytoplasmic
278 298 Membrane
299 314 Extracellular
315 335 Membrane
336 342 Cytoplasmic
343 361 Membrane
362 374 Extracellular
375 396 Membrane
397 410 Cytoplasmic
411 432 Membrane
433 439 Extracellular
440 459 Membrane
460 502 Cytoplasmic

Family and domain data

Database Domain/Family name
InterPro Fru_transpt_5
InterPro MFS_dom
InterPro MFS_sugar_transport-like
InterPro MFS_trans_sf
InterPro Sugar/inositol_transpt
InterPro Sugar_transporter_CS
Pfam Sugar_tr

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