Gene name

SLC22A4 (OCTN1,ETT,UT2H)

Experiment(s)

For this entry:
G1SJV5_RABIT (SLC22A4)
Species Oryctolagus cuniculus
Localization Apical plasma membrane
Reference Garrett Q,Xu S,Simmons PA,Vehige J,Flanagan JL,Willcox MD (2008) Expression and localization of carnitine/organic cation transporter OCTN1 and OCTN2 in ocular epithelium., Invest Ophthalmol Vis Sci, 49, 4844-9.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Cornea
Cell Epithelial cells
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 19 Cytoplasmic
20 39 Membrane
40 143 Extracellular
144 163 Membrane
164 171 Cytoplasmic
172 191 Membrane
192 197 Extracellular
198 218 Membrane
219 228 Cytoplasmic
229 250 Membrane
251 257 Extracellular
258 277 Membrane
278 342 Cytoplasmic
343 363 Membrane
364 373 Extracellular
374 394 Membrane
395 401 Cytoplasmic
402 422 Membrane
423 429 Extracellular
430 450 Membrane
451 460 Cytoplasmic
461 482 Membrane
483 488 Extracellular
489 509 Membrane
510 553 Cytoplasmic

Family and domain data

Database Domain/Family name
InterPro MFS_dom
InterPro MFS_sugar_transport-like
InterPro MFS_trans_sf
InterPro Orgcat_transp/SVOP
InterPro Sugar_transporter_CS
Pfam Sugar_tr

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