Gene name
ANO6 (TMEM16F,ECO:0000303|PubMed:30785399})
Experiment(s)
For this entry:
F1PQ46_CANLF (ANO6)
| Species | Canis lupus familiaris |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Caceres PS,Gravotta D,Zager PJ,Dephoure N,Rodriguez-Boulan E (2019) Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins., Proc Natl Acad Sci U S A, 116, 11796-11805. [PubMed] [DOI] |
| Evidence level | Large-scale proteomics |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 316 | Cytoplasmic |
| 317 | 339 | Membrane |
| 340 | 393 | Extracellular |
| 394 | 411 | Membrane |
| 412 | 471 | Cytoplasmic |
| 472 | 493 | Membrane |
| 494 | 523 | Extracellular |
| 524 | 545 | Membrane |
| 546 | 571 | Cytoplasmic |
| 572 | 592 | Membrane |
| 593 | 688 | Extracellular |
| 689 | 711 | Membrane |
| 712 | 740 | Cytoplasmic |
| 741 | 763 | Membrane |
| 764 | 844 | Extracellular |
| 845 | 865 | Membrane |
| 866 | 928 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Anoct_dimer |
| InterPro | Anoctamin |
| InterPro | Anoctamin-6 |
| Pfam | Anoct_dimer |
| Pfam | Anoctamin |