Gene name
GPRC5A (GPCR5A,RAI3,RAIG1)
Experiment(s)
For this entry:
F1PHN5_CANLF (GPRC5A)
| Species | Canis lupus familiaris |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Caceres PS,Gravotta D,Zager PJ,Dephoure N,Rodriguez-Boulan E (2019) Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins., Proc Natl Acad Sci U S A, 116, 11796-11805. [PubMed] [DOI] |
| Evidence level | Large-scale proteomics |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 32 | Extracellular |
| 33 | 53 | Membrane |
| 54 | 66 | Cytoplasmic |
| 67 | 87 | Membrane |
| 88 | 98 | Extracellular |
| 99 | 119 | Membrane |
| 120 | 130 | Cytoplasmic |
| 131 | 151 | Membrane |
| 152 | 176 | Extracellular |
| 177 | 199 | Membrane |
| 200 | 210 | Cytoplasmic |
| 211 | 232 | Membrane |
| 233 | 243 | Extracellular |
| 244 | 262 | Membrane |
| 263 | 357 | Cytoplasmic |