Gene name
Slc16a1 (Mct1)
Experiment(s)
For this entry:
F1PCQ3_CANLF (Slc16a1)
| Species | Canis lupus familiaris |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Deora AA,Philp N,Hu J,Bok D,Rodriguez-Boulan E (2005) Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia., Proc Natl Acad Sci U S A, 102, 16245-50. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes | Basigin can control localization of MOT1 |
F1PCQ3_CANLF (Slc16a1)
| Species | Canis lupus familiaris |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Tan B,Yatim SMJM,Peng S,Gunaratne J,Hunziker W,Ludwig A (2020) The Mammalian Crumbs Complex Defines a Distinct Polarity Domain Apical of Epithelial Tight Junctions., Curr Biol, 30, 2791-2804.e6. [PubMed] [DOI] |
| Evidence level | Large-scale proteomics |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 16 | Cytoplasmic |
| 17 | 37 | Membrane |
| 38 | 57 | Extracellular |
| 58 | 79 | Membrane |
| 80 | 86 | Cytoplasmic |
| 87 | 106 | Membrane |
| 107 | 111 | Extracellular |
| 112 | 133 | Membrane |
| 134 | 143 | Cytoplasmic |
| 144 | 165 | Membrane |
| 166 | 175 | Extracellular |
| 176 | 195 | Membrane |
| 196 | 261 | Cytoplasmic |
| 262 | 283 | Membrane |
| 284 | 296 | Extracellular |
| 297 | 318 | Membrane |
| 319 | 327 | Cytoplasmic |
| 328 | 348 | Membrane |
| 349 | 352 | Extracellular |
| 353 | 374 | Membrane |
| 375 | 388 | Cytoplasmic |
| 389 | 408 | Membrane |
| 409 | 420 | Extracellular |
| 421 | 442 | Membrane |
| 443 | 498 | Cytoplasmic |