Gene name

SLC16A7 (MCT2)

Experiment(s)

For this entry:
F1P8F7_CANLF (SLC16A7)
Species Canis lupus familiaris
Localization Basolateral plasma membrane
Reference Caceres PS,Gravotta D,Zager PJ,Dephoure N,Rodriguez-Boulan E (2019) Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins., Proc Natl Acad Sci U S A, 116, 11796-11805.
[PubMed] [DOI]
Evidence level Large-scale proteomics
Organ Kidney
Cell MDCK cells (distal tubule)
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 15 Cytoplasmic
16 36 Membrane
37 56 Extracellular
57 78 Membrane
79 85 Cytoplasmic
86 105 Membrane
106 110 Extracellular
111 132 Membrane
133 142 Cytoplasmic
143 164 Membrane
165 174 Extracellular
175 194 Membrane
195 246 Cytoplasmic
247 268 Membrane
269 281 Extracellular
282 303 Membrane
304 312 Cytoplasmic
313 333 Membrane
334 338 Extracellular
339 359 Membrane
360 373 Cytoplasmic
374 394 Membrane
395 405 Extracellular
406 427 Membrane
428 477 Cytoplasmic

Family and domain data

Database Domain/Family name
InterPro MCT
InterPro MCT2
InterPro MFS
InterPro MFS_dom
InterPro MFS_trans_sf
Pfam MFS_1

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