Gene name
SLC44A1
Experiment(s)
For this entry:
E2R949_CANLF (SLC44A1)
| Species | Canis lupus familiaris |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Caceres PS,Gravotta D,Zager PJ,Dephoure N,Rodriguez-Boulan E (2019) Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins., Proc Natl Acad Sci U S A, 116, 11796-11805. [PubMed] [DOI] |
| Evidence level | Large-scale proteomics |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 32 | Cytoplasmic |
| 33 | 54 | Membrane |
| 55 | 217 | Extracellular |
| 218 | 237 | Membrane |
| 238 | 240 | Cytoplasmic |
| 241 | 262 | Membrane |
| 263 | 292 | Extracellular |
| 293 | 314 | Membrane |
| 315 | 334 | Cytoplasmic |
| 335 | 362 | Membrane |
| 363 | 392 | Extracellular |
| 393 | 420 | Membrane |
| 421 | 541 | Cytoplasmic |
| 542 | 563 | Membrane |
| 564 | 568 | Extracellular |
| 569 | 596 | Membrane |
| 597 | 687 | Cytoplasmic |
| 688 | 709 | Membrane |
| 710 | 723 | Extracellular |
Eukaryotic Linear Motif (ELM)
| Start | End | Sequence | Motif |
|---|---|---|---|
| 4 | 7 | SPRR | TRG_ER_diArg_1 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Choline_transptr-like |
| Pfam | Choline_transpo |