Gene name

BST2 (Damp1)

Experiment(s)

For this entry:
BST2_HUMAN (BST2)
Species Homo sapiens
Localization Apical plasma membrane
Reference Rollason R,Korolchuk V,Hamilton C,Jepson M,Banting G (2009) A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells., J Cell Biol, 184, 721-36.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Large intestine
Cell CACO-2 cells (enterocytes)
Notes Apical localization depends on ARHGAP44
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 21 Cytoplasmic
22 44 Membrane
45 166 Extracellular
167 181 Membrane
181 181 Cytoplasmic
Phosphorylation
Glycosylation

Family and domain data

Database Domain/Family name
InterPro BST2
Pfam BST2

Interactions

With (links to EBI) #Exp PubMed links
VPU_HV1B1 7 22072710
LIRA4_HUMAN 2 19564354
CD81_HUMAN 3 32296183
Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.

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