Gene name

Atp1b1 (ATP1B,Atp4b)

Experiment(s)

For this entry:
AT1B1_RAT (Atp1b1)
Species Rattus norvegicus
Localization Basolateral plasma membrane
Reference Vagin O,Turdikulova S,Sachs G (2005) Recombinant addition of N-glycosylation sites to the basolateral Na,K-ATPase beta1 subunit results in its clustering in caveolae and apical sorting in HGT-1 cells., J Biol Chem, 280, 43159-67.
[PubMed] [DOI]
Evidence level Membrane preparation
Organ Kidney
Cell MDCK cells (distal tubule)
Notes YFP was used as an immune epitope for detection
AT1B1_RAT (Atp1b1)
Species Rattus norvegicus
Localization Basolateral plasma membrane
Reference Vagin O,Turdikulova S,Sachs G (2005) Recombinant addition of N-glycosylation sites to the basolateral Na,K-ATPase beta1 subunit results in its clustering in caveolae and apical sorting in HGT-1 cells., J Biol Chem, 280, 43159-67.
[PubMed] [DOI]
Evidence level Membrane preparation
Organ Stomach
Cell HGT-1 cells (parietal cells)
Notes YFP was used as an immune epitope for detection. Localization became apical onse additional N-glycosylation sites were added
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 32 Cytoplasmic
33 53 Membrane
54 304 Extracellular
Phosphorylation
Position Resource
11 29573988
19 36701120
287 36705201
Glycosylation

Family and domain data

Database Domain/Family name
InterPro Na/K_ATPase_sub_beta
InterPro Na/K_ATPase_sub_beta_chordates
InterPro Na/K_ATPase_sub_beta_sf
Pfam Na_K-ATPase

Interactions

With (links to EBI) #Exp PubMed links
RD23B_RAT 2 20178748
Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.

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