Gene name
ATP1A2 (KIAA0778)
Experiment(s)
For this entry:
AT1A2_RAT (ATP1A2)
| Species | Rattus norvegicus |
|---|---|
| Localization | Non polar membrane |
| Reference |
Arakaki X,McCleary P,Techy M,Chiang J,Kuo L,Fonteh AN,Armstrong B,Levy D,Harrington MG (2013) Na,K-ATPase alpha isoforms at the blood-cerebrospinal fluid-trigeminal nerve and blood-retina interfaces in the rat., Fluids Barriers CNS, 10, 14. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Choroid plexus |
| Cell | Ependymal cells |
| Notes | "Protein was mostly found intracellularly |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 96 | Cytoplasmic |
| 97 | 114 | Membrane |
| 115 | 126 | Extracellular |
| 127 | 143 | Membrane |
| 144 | 292 | Cytoplasmic |
| 293 | 310 | Membrane |
| 311 | 318 | Extracellular |
| 319 | 337 | Membrane |
| 338 | 773 | Cytoplasmic |
| 774 | 792 | Membrane |
| 793 | 798 | Extracellular |
| 799 | 817 | Membrane |
| 818 | 847 | Cytoplasmic |
| 848 | 865 | Membrane |
| 866 | 916 | Extracellular |
| 917 | 934 | Membrane |
| 935 | 950 | Cytoplasmic |
| 951 | 968 | Membrane |
| 969 | 984 | Extracellular |
| 985 | 1002 | Membrane |
| 1003 | 1020 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | ATPase_P-typ_cation-transptr_C |
| InterPro | ATPase_P-typ_cation-transptr_N |
| InterPro | ATPase_P-typ_cyto_dom_N |
| InterPro | ATPase_P-typ_P_site |
| InterPro | ATPase_P-typ_TM_dom_sf |
| InterPro | ATPase_P-typ_transduc_dom_A_sf |
| InterPro | HAD-like_sf |
| InterPro | HAD_sf |
| InterPro | P-type_ATPase_IIC |
| InterPro | P_typ_ATPase |
| Pfam | Cation_ATPase_C |
| Pfam | Cation_ATPase_N |