Gene name
PLXNA1 (CHCHD6)
Experiment(s)
For this entry:
A0A5F4BSS4_CANLF (PLXNA1)
| Species | Canis lupus familiaris |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Caceres PS,Gravotta D,Zager PJ,Dephoure N,Rodriguez-Boulan E (2019) Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins., Proc Natl Acad Sci U S A, 116, 11796-11805. [PubMed] [DOI] |
| Evidence level | Large-scale proteomics |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes | The N-terminus of the dog protein is incorrectly extened in UniProt |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 312 | Cytoplasmic |
| 313 | 332 | Membrane |
| 333 | 1555 | Extracellular |
| 1556 | 1577 | Membrane |
| 1578 | 2207 | Cytoplasmic |
Eukaryotic Linear Motif (ELM)
| Start | End | Sequence | Motif |
|---|---|---|---|
| 1946 | 1950 | SLRSR | TRG_ER_diArg_1 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Ig-like_fold |
| InterPro | Ig_E-set |
| InterPro | IPT_dom |
| InterPro | Plexin |
| InterPro | Plexin-A1_Sema |
| InterPro | Plexin_cytoplasmic_RasGAP_dom |
| InterPro | Plexin_repeat |
| InterPro | PSI |
| InterPro | Rho_GTPase_activation_prot |
| InterPro | Semap_dom |
| InterPro | Semap_dom_sf |
| InterPro | TIG1_plexin |
| InterPro | TIG2_plexin |
| InterPro | WD40/YVTN_repeat-like_dom_sf |
| Pfam | Plexin_cytopl |
| Pfam | PSI |
| Pfam | Sema |
| Pfam | TIG |
| Pfam | TIG_2 |
| Pfam | TIG_plexin |